{"id":31749,"date":"2019-05-20T09:00:43","date_gmt":"2019-05-20T16:00:43","guid":{"rendered":"https:\/\/www.avawomen.com\/?p=31749"},"modified":"2019-05-20T05:38:54","modified_gmt":"2019-05-20T12:38:54","slug":"estudio-clinico","status":"publish","type":"post","link":"http:\/\/www.avawomen.com\/avaworld\/es\/estudio-clinico\/","title":{"rendered":"Ava Publica un\u00a0Art\u00edculo Cl\u00ednico Revisado por Expertos"},"content":{"rendered":"

Si hablamos sobre la salud reproductiva femenina y espec\u00edficamente del ciclo menstrual, la investigaci\u00f3n y los conocimientos cient\u00edficos son escasos. Ava se enorgullece de anunciar la publicaci\u00f3n de un art\u00edculo cl\u00ednico revisado por pares<\/a> que arroja una luz sin precedentes sobre este tema.<\/p>\n

\nhttps:\/\/avablog-assets-production.s3.amazonaws.com\/wp-content\/uploads\/2019\/05\/190515_5_signs_of_fertility_80sec_ES.mp4<\/a><\/video><\/div>\n

Este estudio pretend\u00eda comprender qu\u00e9 diferencias en funci\u00f3n de la fase (es decir, cambios fisiol\u00f3gicos en las diferentes fases del ciclo menstrual) podr\u00eda detectar una pulsera respecto a la temperatura de la mu\u00f1eca, la frecuencia card\u00edaca, la variabilidad de la frecuencia card\u00edaca (VFC), la frecuencia respiratoria y la perfusi\u00f3n de la piel. Utilizando m\u00e9todos de inteligencia artificial y aprendizaje autom\u00e1tico, el estudio examin\u00f3 si un algoritmo pod\u00eda identificar con precisi\u00f3n la ventana f\u00e9rtil en tiempo real.<\/p>\n

Lo que quer\u00edamos comprobar con este estudio es si la tecnolog\u00eda de sensores port\u00e1tiles podr\u00eda ayudar a las mujeres a realizar un seguimiento de los cambios fisiol\u00f3gicos a lo largo de sus ciclos menstruales, y si este m\u00e9todo podr\u00eda eliminar la brecha existente entre la costosa detecci\u00f3n de la ovulaci\u00f3n (como las ecograf\u00edas) y el c\u00e1lculo aproximado de la ventana f\u00e9rtil gratuito y menos preciso (como la tradicional medici\u00f3n de la temperatura corporal basal).<\/p>\n

Este estudio es el primero de su clase en investigar m\u00faltiples cambios fisiol\u00f3gicos simult\u00e1neamente a lo largo del ciclo menstrual. Y aprovechando la informaci\u00f3n de la inteligencia artificial y el aprendizaje autom\u00e1tico, el estudio revel\u00f3 que el algoritmo de Ava pod\u00eda detectar los 5 d\u00edas m\u00e1s f\u00e9rtiles en tiempo real.<\/p>\n

Fases del ciclo menstrual <\/strong><\/h2>\n

De acuerdo con investigaciones anteriores, dividimos el ciclo menstrual en las cinco fases siguientes:<\/p>\n

    \n
  • Menstruaci\u00f3n, que comienza el primer d\u00eda del periodo y dura cinco d\u00edas.<\/li>\n
  • Fase folicular, que comienza el primer d\u00eda despu\u00e9s de la menstruaci\u00f3n y se prolonga durante seis d\u00edas antes de la ovulaci\u00f3n (OV\u00a0-6).<\/li>\n
  • Ventana f\u00e9rtil, que comienza cinco d\u00edas antes de la ovulaci\u00f3n y se prolonga hasta la ovulaci\u00f3n (de OV\u00a0-5 a OV).<\/li>\n
  • Fase l\u00fatea temprana, que comienza el primer d\u00eda despu\u00e9s de la ovulaci\u00f3n y se prolonga hasta una semana despu\u00e9s de la ovulaci\u00f3n (de OV\u00a0+1 a OV\u00a0+7).<\/li>\n
  • Fase l\u00fatea tard\u00eda, que comienza ocho d\u00edas despu\u00e9s de la ovulaci\u00f3n (OV +8) y dura hasta el d\u00eda antes del comienzo de la menstruaci\u00f3n.<\/li>\n<\/ul>\n

    Configuraci\u00f3n del estudio <\/strong><\/h2>\n

    Para llevar a cabo este estudio longitudinal prospectivo, seleccionamos a 237 mujeres suizas que intentaban concebir. Todas las participantes usaron la pulsera Ava por la noche mientras dorm\u00edan. Participaron en el estudio durante un m\u00e1ximo de un a\u00f1o o hasta que se quedaron embarazadas. Adem\u00e1s de sincronizar el dispositivo con la aplicaci\u00f3n Ava a diario, las mujeres tambi\u00e9n registraban sus actividades durante las \u00faltimas 24 horas. Por \u00faltimo, las mujeres se hac\u00edan una prueba de orina para detectar el nivel de hormona luteinizante en varios puntos del ciclo en concreto, para poder as\u00ed determinar el final de la ventana f\u00e9rtil. El estudio demostr\u00f3 que se produjeron cambios en las se\u00f1ales fisiol\u00f3gicas durante las diferentes fases del ciclo menstrual y, a continuaci\u00f3n, se prepar\u00f3 un algoritmo de aprendizaje autom\u00e1tico para detectar la ventana f\u00e9rtil.<\/p>\n

    Tras analizar los datos cl\u00ednicos, observamos cambios significativos en las se\u00f1ales fisiol\u00f3gicas, seg\u00fan lo recopilado por el dispositivo a lo largo del ciclo menstrual. Se detectaron cambios en los siguientes signos fisol\u00f3gicos:<\/p>\n

      \n
    • Temperatura de la piel en la mu\u00f1eca<\/li>\n
    • Frecuencia card\u00edaca<\/li>\n
    • Variabilidad de la frecuencia card\u00edaca<\/li>\n
    • Frecuencia respiratoria<\/li>\n
    • Perfusi\u00f3n de la piel<\/li>\n<\/ul>\n

      \u00bfQu\u00e9 significan estos hallazgos en un sentido m\u00e1s amplio? <\/strong><\/h2>\n

      Este art\u00edculo resulta tan interesante porque revela una verdad importante sobre el ciclo menstrual: la temperatura no es lo \u00fanico que cambia durante las diferentes fases del ciclo. De hecho, observamos cambios en cinco se\u00f1ales diferentes a lo largo del ciclo, y al monitorizar esos par\u00e1metros simult\u00e1neamente, podemos detectar cu\u00e1ndo una mujer es f\u00e9rtil. Hasta ahora, lo que se sab\u00eda sobre el ciclo menstrual era que s\u00f3lo cambiaba la temperatura.<\/p>\n

      Pero descubrimos que otras<\/em> cuatro se\u00f1ales fisiol\u00f3gicas tambi\u00e9n<\/em> cambian y que el seguimiento de estas cinco se\u00f1ales juntas nos permite detectar la ventana f\u00e9rtil en tiempo real. Ning\u00fan otro producto realiza el seguimiento de estas cinco se\u00f1ales. Estamos orgullosos de publicar estos hallazgos en una revista revisada por pares, porque demuestra que el algoritmo de seguimiento de la fertilidad multiparam\u00e9trico de Ava es capaz de detectar la ventana f\u00e9rtil con una precisi\u00f3n del 89\u00a0%, adem\u00e1s de ampliar el conocimiento cient\u00edfico de la salud femenina.<\/p>\n

      \u00bfPor qu\u00e9 publica Ava este estudio?<\/strong><\/h2>\n

      La visi\u00f3n de Ava como empresa es convertirnos en un complemento de larga duraci\u00f3n para las mujeres, brind\u00e1ndoles informaci\u00f3n cient\u00edficamente probada y contrastada a lo largo de todas las etapas de su vida reproductiva. Nuestro objetivo consiste en hacerlo a trav\u00e9s de la investigaci\u00f3n cl\u00ednica y la inteligencia artificial. En el pasado, los investigadores m\u00e9dicos pensaban que el cuerpo femenino era ingobernable, complicado o misterioso y en parte, \u00e9sta es la raz\u00f3n por la que todav\u00eda no entendemos del todo las hormonas menstruales y c\u00f3mo afectan a la salud femenina.<\/p>\n

      Nuestra visi\u00f3n es una parte importante del porqu\u00e9 publicamos nuestro art\u00edculo. Y con esta publicaci\u00f3n, no s\u00f3lo tenemos la prueba de que nuestro algoritmo funciona, sino que tambi\u00e9n hemos mejorado la comprensi\u00f3n del cuerpo femenino para todo el mundo.<\/p>\n

       <\/p>\n","protected":false},"excerpt":{"rendered":"

      Si hablamos sobre la salud reproductiva femenina y espec\u00edficamente del ciclo menstrual, la investigaci\u00f3n y […]<\/p>\n","protected":false},"author":6,"featured_media":31712,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[964,955],"tags":[],"yoast_head":"\nAva Publica un\u00a0Art\u00edculo Cl\u00ednico Revisado por Expertos - Ava<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.avawomen.com\/avaworld\/estudio-clinico\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ava Publica un\u00a0Art\u00edculo Cl\u00ednico Revisado por Expertos\" \/>\n<meta property=\"og:description\" content=\"Si hablamos sobre la salud reproductiva femenina y espec\u00edficamente del ciclo menstrual, la investigaci\u00f3n y […]\" \/>\n<meta property=\"og:url\" content=\"http:\/\/www.avawomen.com\/avaworld\/es\/estudio-clinico\/\" \/>\n<meta property=\"og:site_name\" content=\"Ava\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/avabracelet\" \/>\n<meta property=\"article:published_time\" content=\"2019-05-20T16:00:43+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-05-20T12:38:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/avablog-assets-production.s3.amazonaws.com\/wp-offloaded-content\/peer-reviewed-study.png\" \/>\n\t<meta property=\"og:image:width\" content=\"3834\" \/>\n\t<meta property=\"og:image:height\" content=\"3002\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@avawomen\" \/>\n<meta name=\"twitter:site\" content=\"@avawomen\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lindsay Meisel\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Organization\",\"@id\":\"http:\/\/www.avawomen.com\/avaworld\/fr\/#organization\",\"name\":\"Ava Women\",\"url\":\"http:\/\/www.avawomen.com\/avaworld\/fr\/\",\"sameAs\":[\"https:\/\/www.facebook.com\/avabracelet\",\"https:\/\/instagram.com\/avawomen\/\",\"https:\/\/www.linkedin.com\/company\/ava-ag\",\"https:\/\/www.youtube.com\/channel\/UCZ1BceGFRgHo0kIZGaRWHsQ\",\"https:\/\/www.pinterest.com\/avawomen\/\",\"https:\/\/twitter.com\/avawomen\"],\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.avawomen.com\/avaworld\/fr\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.avawomen.com\/avaworld\/wp-content\/uploads\/2015\/12\/Logo_Ava_black_violet_rgb1.png\",\"contentUrl\":\"https:\/\/www.avawomen.com\/avaworld\/wp-content\/uploads\/2015\/12\/Logo_Ava_black_violet_rgb1.png\",\"width\":300,\"height\":80,\"caption\":\"Ava Women\"},\"image\":{\"@id\":\"http:\/\/www.avawomen.com\/avaworld\/fr\/#\/schema\/logo\/image\/\"}},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/www.avawomen.com\/avaworld\/fr\/#website\",\"url\":\"http:\/\/www.avawomen.com\/avaworld\/fr\/\",\"name\":\"Ava\",\"description\":\"Fertility Tracker\",\"publisher\":{\"@id\":\"http:\/\/www.avawomen.com\/avaworld\/fr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.avawomen.com\/avaworld\/fr\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.avawomen.com\/avaworld\/es\/estudio-clinico\/#primaryimage\",\"url\":\"https:\/\/avablog-assets-production.s3.amazonaws.com\/wp-offloaded-content\/peer-reviewed-study.png\",\"contentUrl\":\"https:\/\/avablog-assets-production.s3.amazonaws.com\/wp-offloaded-content\/peer-reviewed-study.png\",\"width\":3834,\"height\":3002},{\"@type\":\"WebPage\",\"@id\":\"http:\/\/www.avawomen.com\/avaworld\/es\/estudio-clinico\/#webpage\",\"url\":\"http:\/\/www.avawomen.com\/avaworld\/es\/estudio-clinico\/\",\"name\":\"Ava Publica un\u00a0Art\u00edculo Cl\u00ednico Revisado por Expertos - 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